擅长： 肿瘤诊断与治疗。

简介： [简 历] 1983年毕业于浙江大学医学院(原浙江医科大学)，曾赴德国、美国等国留学。从事妇产科临床、教学及科研工作三十余年，以妇科肿瘤为主要研究方向。是浙江省有突出贡献中青年专家，澳大利亚西澳大学“Raine杰出访问教授”。曾获浙江省优秀教师、浙江大学首届教学名师奖、“浙江省优秀院长”等称号。主持或参加国家、省部级科研项目数50余项;曾获国家科技进步奖二等奖2项，中华医学奖一等奖和教育部科学技术奖一等奖、二等奖各1项;国家发明专利2项。发表学术论著300余篇，其中SCI源期刊论文100余篇。 现任国家重点(培育)学科和浙江省重点学科-妇产科学学科带头人，国家临床重点专科-妇科学科带头人，浙江省女性生殖健康研究重点实验室主任，浙江省宫颈疾病诊治中心主任，国家级精品课程负责人。是中华医学会妇产科学分会副主任委员，中华医学会妇科肿瘤学分会副主任委员，浙江省医学会妇产科学分会主任委员，浙江省抗癌协会妇科肿瘤专业委员会主任委员等。担任人民卫生出版社国家规划教材《妇产科学》专升本教材(第一、第二版)主编、5年制教材(第八版)主编、长学制教材编者，是中华医学杂志英文版、中华医学杂志、中华妇产科杂志等10余种杂志的编委。 近年发表的SCI文献： (1)Interleukin-7 and Suppression of Local Peritoneal Immunity in Ovarian Carcinoma. Int J Gynecol Obstet 2004;85:151-158. (通讯作者) (2)Effect of Interleukin-7 Gene Transfection into Ovarian Carcinoma Cell Line SKOV3 In vitro and In vivo. Gynocol Oncol 2004;92(2)：578-585. (通讯作者) (3)Ovarian cacinoma cells inhibit T cell proliferation: suppression of IL-12 receptor β and γ expression and their JAK-STAT signaling. Life Science 2004;74(14): 1739-1749. (通讯作者) (4)VEGF And Ovarian Cancer Cell Supernatant Activate Signal Transducers And Activators Of Transcription (STATs) Via VEGF Receptor-2 (KDR) In Human Hemopoietic Progenitor Cells. Gynocol Oncol 2004;94:125-133(通讯作者) (5)VEGF,VEGFRs expressions and activated STATs in ovarian epithelial carcinoma. Gynecol Oncol,2004;94:630-635(通讯作者) (6)Impaired mixed lymphocyte reaction in intrahepatic cholestasis of pregnancy. Gynecol Obstet Invest,2002:54:191-195 (7)Sedentary behaviours and epithelial ovarian cancer risk. Cancer Causes and Control,2004;15:83-89 (8)The value of curettage in diagnosis of endometrial hyperplasia. Gynecol Oncol. 2002;84(1):135-139. (通讯作者) (9)Lack of mutation in tumor-suppressor gene p53 in gestational trophoblastic tumours. Br J Cancer 1996;73:1216-1219. (10)Cell culture of biopsied endometriomas after danazol/hormonal therapy:A study of growth features and fertility effects. Indian J Exper Bio.2000;38:1192-1200. (11)Ovarian Carcinoma Cells Effectively Inhibit Differentiation And Maturation Of Dendritic Cells Derived From Hematopoietic Progenitor Cells In Vitro. Cancer Investigation, in printing. (通讯作者) (12) Mismatch repair gene promoter methylation and expression in hydatidiform moles. Arch Gynecol Obstet. 2005;272:35-39; (通讯作者) (13) PTEN Promoter Methylation and Protein Expression in Normal Early Placentas and Hydatidiform Moles. J Soc Gynecol Investig 2005;12:214 –7 (14) Proportion of CD4+CD25+ regulatory T cell is increased in the paitients with ovarian cancer. Cancer Investigation. 2005, in printing. (通讯作者) (15)Growth inhibition of interleukin-2 receptor gene-tranduced peripheral blood lymphocytes on human ovarian cancer cells. Chin Med J, 2001; 114 (3): 303-307. [主攻学科] 妇产科 [研究方向] 卵巢癌与腹腔免疫缺陷及其机制，宫颈癌发生的免疫学和分子遗传学机制，妊娠滋养细胞疾病发病的分子遗传学机制